Bone marrow transplant for Thalassemia cost in India is 25000-35000 USD with 28-45 days hospital stay. Thalassemia is a inherited blood disorder disease in which red blood cell production is less and also destruction is more. If left untreated more than 90 percent of these patients die by age of two years. These patients needed life-long blood transfusion every 3-4 weeks. Over a period of time outcome is overload of iron in the blood due to repeatedly transfusion affecting the liver and heart causing death.
Thanks to Bone Marrow Transplant is the only curative option in Thalassemia patients.
Bone marrow transplantation (BMT) or Hematopoietic stem cell transplant is a non-surgical procedure that infuses healthy cells into the body. It is used to treat blood disorders like Aplastic anaemia , Sickle cell anaemia and Thalassemia major. In the procedure, healthy stem cells taken from the bone marrow , blood, or umbilical cord are used to replace cancerous or faulty blood cells. The stem cell transplant can be of three types - Autologous (Self-donate stem cells), Allogeneic (Matched / stem cells from a donor), or Syngeneic (Only possible for identical twins).
Procedure Needed : Allogeneic Bone Marrow (Stem Cell) Transplant.
Allogeneic bone marrow or stem cell transplant (Matched / stem cells from a donor). Allogeneic Bone Marrow Transplant (BMT) is typically recommended to treat certain medical conditions where the bone marrow is dysfunctional.
To look for options for allogenic bone marrow transplant HLA typing of patient and sibling should be performed.
If there is any sibling they should be tested for HLA typing. HLA typing of parents can be done as some time we are getting full match with parents. In case of non-availability of familial donor unrelated matched donor may be considered.
If this procedure is performed with half-matched stem cells, it is called haploidentical bone marrow transplant . Careful preparation is required for successful results, which include a conditioning for patients with Thalassemia . It might take up to several weeks for healthy , cells to grow after the bone marrow transplant procedure.
Most Important Pre-requisite: Stem cell donor (It could be HLA matched sibling/ Parents: HLA typing of patient and sibling/ Parents is needed to identify suitable donor).
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